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JOURNAL
OF
SPORTS SCIENCE &
MEDICINE
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Research
article
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FUNCTIONAL STATUS AND INFLAMMATION AFTER PRESEASON TRAINING PROGRAM IN PROFESSIONAL AND RECREATIONAL SOCCER PLAYERS: A PROTEOMIC APPROACH |
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Francisco J. Martín-Sánchez2, José María Villalón3, José J. Zamorano-León1, Luis Fernández Rosas3, Ricardo Proietti1, Petra J. Mateos-Caceres1, Juan J. González-Armengol2, Pedro Villarroel2, Carlos Macaya1 and Antonio J. López-Farré1  |
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1Cardiovascular Research Unit, Cardiology Department and 2Emergency Unit, Hospital Clínico San Carlos, 3Medical Department of Atlético de Madrid Football Club, Madrid, Spain |
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© Journal of Sports Science and Medicine (2011) 10, 45 - 51 |
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| ABSTRACT | |||
| The purpose of the study was to determine if an intensive pre-
season training program modifies the inflammatory status in professional
soccer players and if this inflammatory profile may be associated with the
physical state. We compared plasma protein biomarkers, using proteomics,
and the physiological state and cardiac function in 12 professional soccer
players and 9 recreational soccer players. Reduced cardiac low frequency
[LF] after the pre- season training program previous competition with respect
to recreational soccer players was found. No differences were found in cardiac
high frequency, cardiac high frequency/low frequency ratio, tension index
and oxygen volume consumption. Alpha-1-antitrypsin isotype-3, fibrinogen-gamma
isotypes-1, 2 and 3 and vitamin-D-binding protein isotype-1 were reduced
in professionals players compared with those in recreational players. However,
an increased content of alpha-1-antitrypsin isotype-6 and alpha-1-antichymotrypsin
1 and 4 were found in professional soccer players. Spearman´s analysis showed
a positive correlation between LF and fibrinogen-gamma chain isotype 3;
but LF was negatively correlated with alpha-antichymotrypsin isotype 4.
Professional soccer players submitted to an intensive training showed differences
in the content of plasma proteins associated with inflammatory/oxidative
stress and thrombosis with respect to recreational soccer players. Proteomics
analysis in combination with the analysis of cardiac function assessment
may be useful to know more in depth molecular processes associated with
sport and intensive exercise.
Key words: Inflammation, proteomics, soccer, physical performance. |
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